ZFIN ID: ZDB-GENE-070112-482
Gene Name: D-2-hydroxyglutarate dehydrogenase
Gene Symbol: d2hgdh
Previous Name: zgc:158661
Location: Chr: 2 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa16838 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17480 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH d2hgdh HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    D-2-hydroxyglutaric aciduria D-2-hydroxyglutaric aciduria 600721
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process oxidation-reduction process (more)
    Cellular Component mitochondrion (more)
    Molecular Function catalytic activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR004113 (1)
  • InterPro:IPR006094 (1)
  • InterPro:IPR016164 (1)
  • InterPro:IPR016166 (1)
  • InterPro:IPR016167 (1)
  • InterPro:IPR016169 (1)
  • InterPro:IPR016171 (1)
  • PROSITE:PS51387 (1)
  • Pfam:PF01565 (1)
  • Pfam:PF02913 (1)
  • EC:1.1.99.- (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA d2hgdh-001 (1) 1833
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM d2hgdh No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    d2hgdhContained in: [BAC] CH211-62C1 (1) (order this)
    d2hgdhEncodes: [cDNA] MGC:158661 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001080597 (1) 1836bp
    Genomic GenBank:CT476817 (1) 173555bp
    Select Tool
    Polypeptide UniProtKB:A1L258 (1) 533aa
    Sequence Clusters UniGene:86117 (1)
    Sequence Information (all 12)
    OTHER d2hgdh GENE PAGES
  • Gene:565889 (1)
  • VEGA:OTTDARG00000025849 (1)
  • Ensembl(GRCz10):ENSDARG00000060210 (1)
  • ORTHOLOGY for d2hgdh (Chr: 2)
    Species Symbol Chromosome Accession # Evidence
    Human D2HGDH 2
  • Gene:728294
  • OMIM:609186
  • HGNC:28358
  • Amino acid sequence comparison (1)
    Mouse D2hgdh 1
  • MGI:2138209
  • Gene:98314
  • Amino acid sequence comparison (1)
    Download Curated Orthology
    CITATIONS (15)