ZFIN ID: ZDB-GENE-070112-482
Gene Name: D-2-hydroxyglutarate dehydrogenase
Gene Symbol: d2hgdh
Previous Name: zgc:158661
Location: Chr: 2 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
sa16838 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17480 Point Mutation ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH d2hgdh HUMAN ORTHOLOG 
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    D-2-hydroxyglutaric aciduria D-2-hydroxyglutaric aciduria 600721
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process oxidation-reduction process (more)
    Cellular Component mitochondrion (more)
    Molecular Function catalytic activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR004113 (1)
  • InterPro:IPR006094 (1)
  • InterPro:IPR016164 (1)
  • InterPro:IPR016166 (1)
  • InterPro:IPR016167 (1)
  • InterPro:IPR016169 (1)
  • InterPro:IPR016171 (1)
  • PROSITE:PS51387 (1)
  • Pfam:PF01565 (1)
  • Pfam:PF02913 (1)
  • EC:1.1.99.- (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA d2hgdh-001 (1) 1833
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM d2hgdh No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    d2hgdhContained in: [BAC] CH211-62C1 (1) (order this)
    d2hgdhEncodes: [cDNA] MGC:158661 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001080597 (1) 1836bp
    Genomic RefSeq:NW_003040989 (1) 505747bp Blast at MegaBLAST
    Polypeptide UniProtKB:A1L258 (1) 533aa
    Sequence Clusters UniGene:86117 (1)
    Sequence Information (all 14)
    OTHER d2hgdh GENE PAGES 
  • Gene:565889 (1)
  • VEGA:OTTDARG00000025849 (1)
  • Ensembl(GRCz10):ENSDARG00000060210 (1)
  • ORTHOLOGY for d2hgdh (Chr: 2) 
    Species Symbol Chromosome Accession # Evidence
    Human D2HGDH 2
  • Gene:728294
  • OMIM:609186
  • HGNC:28358
  • Amino acid sequence comparison (1)
    Mouse D2hgdh 1
  • MGI:2138209
  • Gene:98314
  • Amino acid sequence comparison (1)
    Download Curated Orthology
    CITATIONS (15)