Gene

gnb5a

ID
ZDB-GENE-070112-342
Name
guanine nucleotide binding protein (G protein), beta 5a
Symbol
gnb5a Nomenclature History
Previous Names
  • zgc:158678
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Is predicted to enable signaling receptor complex adaptor activity. Involved in G protein-coupled receptor signaling pathway and dopamine receptor signaling pathway. Acts upstream of or within heart contraction; optokinetic behavior; and swimming behavior. Predicted to be located in membrane. Predicted to be part of heterotrimeric G-protein complex. Orthologous to human GNB5 (G protein subunit beta 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Xu et al., 2012
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gnb5a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
intellectual developmental disorder with cardiac arrhythmia Alliance Intellectual developmental disorder with cardiac arrhythmia 617173
Language delay and ADHD/cognitive impairment with or without cardiac arrhythmia 617182
Associated With gnb5a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019775 WD40 repeat, conserved site
Domain IPR001632 G-protein, beta subunit
Family IPR016346 Guanine nucleotide-binding protein, beta subunit
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Repeat IPR001680 WD40 repeat
Repeat IPR020472 G-protein beta WD-40 repeat
Domain Details Per Protein
Protein Length G-protein, beta subunit G-protein beta WD-40 repeat Guanine nucleotide-binding protein, beta subunit WD40 repeat WD40 repeat, conserved site WD40-repeat-containing domain superfamily WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:A1L271 355
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations