ZFIN ID: ZDB-GENE-070112-202
Gene Name: diablo, IAP-binding mitochondrial protein b
Gene Symbol: diablob    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: zgc:158776

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 21 Mapping Details/Browsers
Description: Predicted to be involved in activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; intrinsic apoptotic signaling pathway in response to oxidative stress; and neuron apoptotic process. Predicted to localize to mitochondrion. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 64. Orthologous to human DIABLO (diablo IAP-binding mitochondrial protein).
Genome Resources: Alliance (1),  Gene:570425 (1),  Ensembl(GRCz11):ENSDARG00000014956 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa43631 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45736 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH diablob HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    autosomal dominant nonsyndromic deafness 64 Alliance Deafness, autosomal dominant 64 614152
    DISEASE ASSOCIATED WITH diablob VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process activation of cysteine-type endopeptidase activity involved in apoptotic process (more)
    Cellular Component mitochondrion (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA diablob-201 (1)    Ensembl 1104
    diablob-202 (1)    Ensembl 930
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM diablob No data available
    MARKER RELATIONSHIPS
    diablob Contained in: [BAC] DKEY-62A13 (1) (order this)
    diablob Encodes: [cDNA] MGC:158776 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001243034 (1)
    Genomic GenBank:CR391925 (1) 159324 nt
    Select Tool
    Polypeptide UniProtKB:F1R484 (1) 247 aa
    Sequence Information (all 14)
    ORTHOLOGY for diablob ( Chr: 21 )
    CITATIONS (18)