Gene
dnai1.2
- ID
- ZDB-GENE-070112-1302
- Name
- dynein, axonemal, intermediate chain 1, paralog 2
- Symbol
- dnai1.2 Nomenclature History
- Previous Names
-
- zgc:158666
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to contribute to ATP-dependent microtubule motor activity, plus-end-directed. Predicted to be involved in cilium movement and outer dynein arm assembly. Predicted to localize to outer dynein arm. Human ortholog(s) of this gene implicated in Kartagener syndrome and primary ciliary dyskinesia 1. Orthologous to human DNAI1 (dynein axonemal intermediate chain 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| primary ciliary dyskinesia 1 | Alliance | Ciliary dyskinesia, primary, 1, with or without situs inversus | 244400 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Dynein Intermediate Chain | WD40 repeat | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:A1L262
|
660 | ||||
|
UniProtKB:A0A8M3AM55
|
425 | ||||
|
UniProtKB:A0A8M9PCP6
|
609 | ||||
|
UniProtKB:A0A8M3B4P0
|
660 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
dnai1.2-201
(1)
|
Ensembl | 2,312 nt | ||
| mRNA |
dnai1.2-202
(1)
|
Ensembl | 641 nt |
Interactions and Pathways
No data available
Plasmids
No data available