Gene

hs6st1b

ID
ZDB-GENE-070103-2
Name
heparan sulfate 6-O-sulfotransferase 1b
Symbol
hs6st1b Nomenclature History
Previous Names
  • 6-ost-1b (1)
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Predicted to have heparan sulfate 6-O-sulfotransferase activity. Predicted to be involved in heparan sulfate proteoglycan biosynthetic process, enzymatic modification. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 15 with or without anosmia. Is expressed in several structures, including hindbrain neural keel; immature eye; nervous system; pancreatic bud; and presumptive floor plate. Orthologous to human HS6ST1 (heparan sulfate 6-O-sulfotransferase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from Cadwallader et al., 2006
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hs6st1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hypogonadotropic hypogonadism 15 with or without anosmia Alliance {Hypogonadotropic hypogonadism 15 with or without anosmia} 614880
Associated With hs6st1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR005331 Sulfotransferase
Family IPR010635 Heparan sulphate 6-sulfotransferase/Protein-tyrosine sulfotransferase
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length Heparan sulphate 6-sulfotransferase/Protein-tyrosine sulfotransferase P-loop containing nucleoside triphosphate hydrolase Sulfotransferase
UniProtKB:A0MGZ5 407
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations