Gene

aass

ID
ZDB-GENE-061220-8
Name
aminoadipate-semialdehyde synthase
Symbol
aass Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to have saccharopine dehydrogenase activity. Predicted to be involved in lysine biosynthetic process via aminoadipic acid. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in hyperlysinemia. Orthologous to human AASS (aminoadipate-semialdehyde synthase).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With aass Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hyperlysinemia Alliance Hyperlysinemia 238700
Associated With aass Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR005097 Saccharopine dehydrogenase, NADP binding domain
Domain IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain
Domain IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal
Domain IPR032095 Saccharopine dehydrogenase, C-terminal
Homologous_superfamily IPR036291 NAD(P)-binding domain superfamily
Domain Details Per Protein
Protein Length Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal NAD(P)-binding domain superfamily Saccharopine dehydrogenase, C-terminal Saccharopine dehydrogenase, NADP binding domain
UniProtKB:F8W3V5 220
UniProtKB:E7FD66 935
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations