ZFIN ID: ZDB-GENE-061220-5
Gene Name: ATPase copper transporting beta
Gene Symbol: atp7b    Nomenclature History

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Previous Name: si:dkey-276l13.3 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have copper transmembrane transporter activity, phosphorylative mechanism. Predicted to be involved in cellular copper ion homeostasis and copper ion export. Predicted to localize to perinuclear region of cytoplasm and trans-Golgi network. Is expressed in head and liver. Human ortholog(s) of this gene implicated in Wilson disease. Orthologous to human ATP7B (ATPase copper transporting beta).
Genome Resources: Alliance (1),  Gene:556499 (1),  Ensembl(GRCz11):ENSDARG00000058145 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
PHENOTYPE No data available
DISEASE ASSOCIATED WITH atp7b HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Wilson disease Alliance Wilson disease 277900
DISEASE ASSOCIATED WITH atp7b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cation transport (more)
Cellular Component integral component of membrane (more)
Molecular Function ATPase-coupled cation transmembrane transporter activity (more)
GO Terms (all 14)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA atp7b-201 (1)    Ensembl 4092
Browsers: NCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM atp7b No data available
MARKER RELATIONSHIPS
atp7b Contained in: [BAC] DKEY-276L13 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:XM_009302193 (1)
Genomic GenBank:BX511272 (1) 208912 nt Blast at MegaBLAST
Polypeptide UniProtKB:I3ITM6 (1) 1363 aa
Sequence Information (all 8)
ORTHOLOGY for atp7b ( Chr: 6 )
CITATIONS (23)