ZFIN ID: ZDB-GENE-061215-37
Gene Name: iduronate 2-sulfatase
Gene Symbol: ids
Sequence Ontology ID : SO:0000704

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Previous Name: zgc:158245

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Location: Chr: 14 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits iduronate-2-sulfatase activity; involved in several processes, including animal organ development, cell surface receptor signaling pathway, and chordate embryonic development; localizes to  ...
GENE EXPRESSION
All Expression Data: Fig. 3 from Moro et al., 2010
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ia200 Small Deletion Unknown Unknown CRISPR
la027504Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa42383 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 5 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH ids HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    mucopolysaccharidosis II Mucopolysaccharidosis II 309900
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process canonical Wnt signaling pathway involved in heart development (more)
    Cellular Component cytoplasm (more)
    Molecular Function iduronate-2-sulfatase activity (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000917 (1)
  • InterPro:IPR017849 (1)
  • InterPro:IPR017850 (1)
  • InterPro:IPR024607 (1)
  • InterPro:IPR035874 (1)
  • PROSITE:PS00149 (1)
  • Pfam:PF00884 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ids-001 (1) 1978
    ncRNA ids-002 (1) 779
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ids No data available
    MARKER RELATIONSHIPS
    idsContained in: [BAC] CH211-42H24 (1) (order this)
    idsEncodes: [cDNA] MGC:158245 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001080068 (1) 1978bp
    Genomic GenBank:CR774199 (1) 162722bp
    Select Tool
    Polypeptide UniProtKB:A0ST40 (1) 561aa
    Sequence Clusters UniGene:133404 (1)
    Sequence Information (all 14)
    OTHER ids GENE PAGES
  • Alliance (1)
  • Gene:559959 (1)
  • VEGA:OTTDARG00000028377 (1)
  • Ensembl(GRCz11):ENSDARG00000071699 (2)
  • ORTHOLOGY for ids (Chr: 14)
    CITATIONS (19)