Gene

f2rl1.1

ID
ZDB-GENE-061215-140
Name
coagulation factor II (thrombin) receptor-like 1, tandem duplicate 1
Symbol
f2rl1.1 Nomenclature History
Previous Names
  • f2rl1
  • par2a (1)
  • par2-21d (1)
  • zgc:158264
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have G protein-coupled receptor activity. Predicted to be involved in positive regulation of Rho protein signal transduction and positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway. Predicted to localize to integral component of plasma membrane. Is expressed in thrombocyte. Human ortholog(s) of this gene implicated in asthma; chronic obstructive pulmonary disease; and respiratory allergy. Orthologous to human F2RL1 (F2R like trypsin receptor 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With f2rl1.1 Human Ortholog
No data available
Associated With f2rl1.1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR017452 GPCR, rhodopsin-like, 7TM
Family IPR000276 G protein-coupled receptor, rhodopsin-like
Family IPR002281 Protease-activated receptor 2
Family IPR003912 Protease-activated receptor
Domain Details Per Protein
Protein Length GPCR, rhodopsin-like, 7TM G protein-coupled receptor, rhodopsin-like Protease-activated receptor Protease-activated receptor 2
UniProtKB:A1A5V5 380
UniProtKB:E9QBJ7 270
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations