Gene

atp13a2

ID
ZDB-GENE-061215-126
Name
ATPase cation transporting 13A2
Symbol
atp13a2 Nomenclature History
Previous Names
  • im:7147302
  • zgc:136762
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have ATP binding activity; ATPase activity; and metal ion binding activity. Involved in cerebellum formation; chordate embryonic development; and locomotory behavior. Predicted to localize to integral component of membrane. Is expressed in brain. Used to study Parkinson's disease and amyotrophic lateral sclerosis. Human ortholog(s) of this gene implicated in Kufor-Rakeb syndrome; Parkinson's disease; and hereditary spastic paraplegia. Orthologous to human ATP13A2 (ATPase cation transporting 13A2).
Genome Resources
Note
None
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With atp13a2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Kufor-Rakeb syndrome Alliance Kufor-Rakeb syndrome 606693
Spastic paraplegia 78, autosomal recessive 617225
Associated With atp13a2 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004014 Cation-transporting P-type ATPase, N-terminal
Family IPR001757 P-type ATPase
Family IPR006544 P-type ATPase, subfamily V
Homologous_superfamily IPR008250 P-type ATPase, A domain superfamily
Homologous_superfamily IPR023214 HAD superfamily
Homologous_superfamily IPR023298 P-type ATPase, transmembrane domain superfamily
Homologous_superfamily IPR023299 P-type ATPase, cytoplasmic domain N
Homologous_superfamily IPR036412 HAD-like superfamily
PTM IPR018303 P-type ATPase, phosphorylation site
Domain Details Per Protein
Protein Length Cation-transporting P-type ATPase, N-terminal HAD-like superfamily HAD superfamily P-type ATPase P-type ATPase, A domain superfamily P-type ATPase, cytoplasmic domain N P-type ATPase, phosphorylation site P-type ATPase, subfamily V P-type ATPase, transmembrane domain superfamily
UniProtKB:A1A5E5 1170
UniProtKB:E9QDX3 75
UniProtKB:A0A2R8QKM0 1170
UniProtKB:F1QLT2 1170
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations