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General Information
ZIRC
ZFIN ID: ZDB-GENE-061214-5
Gene Name: potassium voltage-gated channel, KQT-like subfamily, member 1.1
Gene Symbol: kcnq1.1
Sequence Ontology ID : SO:0000704

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Previous Names: kcnq1, zgc:158384

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(Including Attributions)
Location: Chr: 7 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have calmodulin binding activity and delayed rectifier potassium channel activity. Involved in kidney development and renal filtration. Predicted to localize to the voltage-gated  ...
GENE EXPRESSION
All Expression Data: 6 figures from 5 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la026114Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la026115Tg Transgenic Insertion Unknown Unknown DNA
    la026116Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa27036 Point Mutation Unknown Splice Site ENU
    sa38635 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40998 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45295 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: Fig. 4 from Liu et al., 2011
    Observed in:
    DISEASE ASSOCIATED WITH kcnq1.1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    familial atrial fibrillation Atrial fibrillation, familial, 3 607554
    Jervell-Lange Nielsen syndrome Jervell and Lange-Nielsen syndrome 220400
    long QT syndrome 1 Long QT syndrome 1 192500
    {Long QT syndrome 1, acquired, susceptibility to} 192500
    short QT syndrome Short QT syndrome 2 609621
    DISEASE ASSOCIATED WITH kcnq1.1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process kidney development (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ion channel activity (more)
    GO Terms (all 14)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA kcnq1-201 (1) 2691
    kcnq1-202 (1) 1843
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM kcnq1.1 No data available
    MARKER RELATIONSHIPS
    kcnq1.1Contained in: [BAC] DKEY-7P8 (order this)
    kcnq1.1Encodes: [cDNA] MGC:158384 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001123242 (1) 2475bp
    Genomic GenBank:AL928843 (1) 179577bp
    Select Tool
    Polypeptide UniProtKB:B0R0K2 (1) 655aa
    Sequence Clusters UniGene:90346 (1)
    Sequence Information (all 14)
    ORTHOLOGY for kcnq1.1 (Chr: 7)
    CITATIONS (26)