Gene

trpm2

ID
ZDB-GENE-061214-4
Name
transient receptor potential cation channel, subfamily M, member 2
Symbol
trpm2 Nomenclature History
Previous Names
  • si:ch73-263b18.1
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Exhibits calcium ion binding activity; ligand-gated calcium channel activity; and mono-ADP-D-ribose binding activity. Involved in calcium ion transmembrane transport and protein homotetramerization. Localizes to integral component of plasma membrane. Is expressed in integument; keratinocyte; nervous system; and solid lens vesicle. Orthologous to human TRPM2 (transient receptor potential cation channel subfamily M member 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With trpm2 Human Ortholog
No data available
Associated With trpm2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001870 B30.2/SPRY domain
Domain IPR003877 SPRY domain
Domain IPR003879 Butyrophylin-like, SPRY domain
Domain IPR005821 Ion transport domain
Domain IPR006574 SPRY-associated
Domain IPR007111 NACHT nucleoside triphosphatase
Domain IPR029495 NACHT-associated domain
Domain IPR041075 NOD2, winged helix domain
Domain IPR041267 NACHT, LRR and PYD domains-containing protein, helical domain HD2
Domain IPR041491 TRPM, SLOG domain
Family IPR029594 Transient receptor potential cation channel subfamily M member 2
Homologous_superfamily IPR013320 Concanavalin A-like lectin/glucanase domain superfamily
Homologous_superfamily IPR015797 NUDIX hydrolase-like domain superfamily
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR032675 Leucine-rich repeat domain superfamily
Homologous_superfamily IPR043136 B30.2/SPRY domain superfamily
Repeat IPR001611 Leucine-rich repeat
Domain Details Per Protein
Protein Length B30.2/SPRY domain B30.2/SPRY domain superfamily Butyrophylin-like, SPRY domain Concanavalin A-like lectin/glucanase domain superfamily Ion transport domain Leucine-rich repeat Leucine-rich repeat domain superfamily NACHT-associated domain NACHT, LRR and PYD domains-containing protein, helical domain HD2 NACHT nucleoside triphosphatase NOD2, winged helix domain NUDIX hydrolase-like domain superfamily P-loop containing nucleoside triphosphate hydrolase SPRY-associated SPRY domain Transient receptor potential cation channel subfamily M member 2 TRPM, SLOG domain
UniProtKB:S5TZ89 1470
UniProtKB:A0A5H1ZRI9 197
UniProtKB:A0A0R4IMY7 1470
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations