Gene
trpm4b.2
- ID
- ZDB-GENE-061214-2
- Name
- transient receptor potential cation channel, subfamily M, member 4b, transient receptor potential cation channel, subfamily M, member 4b, tandem duplicate 2
- Symbol
- trpm4b.2 Nomenclature History
- Previous Names
-
- trpm4b1 (1)
- trpm4c
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have calcium activated cation channel activity. Predicted to be involved in several processes, including cardiac conduction; regulation of T cell cytokine production; and vasoconstriction. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in erythrokeratodermia variabilis and progressive familial heart block type IB. Orthologous to human TRPM4 (transient receptor potential cation channel subfamily M member 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| erythrokeratodermia variabilis et progressiva 6 | Alliance | Erythrokeratodermia variabilis et progressiva 6 | 618531 |
| progressive familial heart block type IB | Alliance | Progressive familial heart block, type IB | 604559 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Ion transport domain | TRPM, SLOG domain |
|---|---|---|---|
|
UniProtKB:F1RC25
|
1222 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance