Gene

pkn2

ID
ZDB-GENE-061207-42
Name
protein kinase N2
Symbol
pkn2 Nomenclature History
Previous Names
  • si:ch211-83f14.1
  • wu:fa97c07
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have protein serine/threonine kinase activity. Involved in embryonic viscerocranium morphogenesis and heart development. Predicted to localize to several cellular components, including cleavage furrow; midbody; and nucleus. Orthologous to human PKN2 (protein kinase N2).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Fitzgerald et al., 2015
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pkn2 Human Ortholog
No data available
Associated With pkn2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000008 C2 domain
Domain IPR000719 Protein kinase domain
Domain IPR000961 AGC-kinase, C-terminal
Domain IPR011072 HR1 rho-binding domain
Domain IPR017892 Protein kinase, C-terminal
Domain IPR037313 Serine/threonine-protein kinase N, first HR1 domain
Domain IPR037784 Serine/threonine-protein kinase N, C2 domain
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR036274 HR1 repeat superfamily
Domain Details Per Protein
Protein Length AGC-kinase, C-terminal C2 domain HR1 repeat superfamily HR1 rho-binding domain Protein kinase, ATP binding site Protein kinase, C-terminal Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site Serine/threonine-protein kinase N, C2 domain Serine/threonine-protein kinase N, first HR1 domain
UniProtKB:A0A0R4IJZ0 970
UniProtKB:A0A2R8QFC7 1005
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations