ZFIN ID: ZDB-GENE-061130-2
Gene Name: TYRO protein tyrosine kinase binding protein
Gene Symbol: tyrobp
Previous Name: dap12 (1)
Location: Chr: 16 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
  intestine, kidney, liver, lymphocyte (all 6) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTSNo data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH tyrobp HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
Nasu-Hakola disease 221770
GENE ONTOLOGY
Ontology GO Term
Biological Process phosphatidylinositol 3-kinase signaling (more)
Cellular Component integral component of membrane (more)
Molecular Function protein binding (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR026200 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA tyrobp-001 (1) 796
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM tyrobp No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    tyrobpContained in: [BAC] DKEY-29H14 (order this), DKEY-104N21 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001100103 (1) 796bp
    Genomic GenBank:BX323874 256605bp Blast at MegaBLAST
    Polypeptide UniProtKB:A0A0R4IYU7 (1) 116aa
    Sequence Clusters UniGene:141624 (1)
    Sequence Information (all 13)
    OTHER tyrobp GENE PAGES
  • Gene:100101461 (1)
  • VEGA:OTTDARG00000027672 (1)
  • Ensembl(GRCz10):ENSDARG00000094894 (1)
  • ORTHOLOGY for tyrobp (Chr: 16)
    Species Symbol Chromosome Accession # Evidence
    Human TYROBP 19
  • Gene:7305
  • OMIM:604142
  • HGNC:12449
  • Amino acid sequence comparison (1)
    Mouse Tyrobp 7
  • MGI:1277211
  • Gene:22177
  • Amino acid sequence comparison (1)
    Download Curated Orthology
    CITATIONS (8)