ZFIN ID: ZDB-GENE-061130-2
Gene Name: TYRO protein tyrosine kinase binding protein
Gene Symbol: tyrobp
Previous Name: dap12 (1)
Location: Chr: 16   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
  intestine, kidney, liver, lymphocyte (all 6) expand
MUTANTS AND TARGETED KNOCKDOWNS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH tyrobp HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
Nasu-Hakola disease 221770
GENE ONTOLOGY
Ontology GO Term
Biological Process phosphatidylinositol 3-kinase signaling (more)
Cellular Component intracellular (more)
Molecular Function protein binding (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR026200 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA tyrobp-001 (1) 796
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tyrobp No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    tyrobp Contained in: [BAC] DKEY-29H14 (order this), DKEY-104N21 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001100103 (1) 798 bp
    Genomic GenBank:BX323874 256605 bp Blast at MegaBLAST
    Polypeptide UniProtKB:A6Y956 (1) 115 aa
    Sequence Clusters UniGene:141624 (1)
    Sequence Information (all 12)
    OTHER tyrobp GENE PAGES
  • Gene:100101461 (1)
  • VEGA:OTTDARG00000027672 (1)
  • Ensembl(Zv9):ENSDARG00000094894 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA
    Zebrafish tyrobp 16  
    Human TYROBP 19 (19q13.1)
  • OMIM:604142
  • Gene:7305
  • Mouse Tyrobp 7 ( 17.45 cM)
  • MGI:1277211
  • Gene:22177
  • Orthology Details
    CITATIONS (8)