Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-061130-2
Gene Name: TYRO protein tyrosine kinase binding protein
Gene Symbol: tyrobp
Previous Name: dap12 (1)
Nomenclature History
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
  intestine, kidney, liver, lymphocyte (all 6) expand
MUTANTS AND TARGETED KNOCKDOWNS No data available
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Nasu-Hakola disease 221770
GENE ONTOLOGY
Ontology GO Term
Biological Process phosphatidylinositol 3-kinase signaling (more)
Cellular Component intracellular (more)
Molecular Function protein binding (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (bp) Analysis
mRNA tyrobp-001 (1) 796
GENE PRODUCT DESCRIPTION
ANTIBODIES No data available
CONSTRUCTS WITH SEQUENCES FROM tyrobp No data available
SEGMENT (CLONE AND PROBE) RELATIONSHIPS
tyrobp Contained in: [BAC] DKEY-29H14, DKEY-104N21
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001100103 (1) 798 bp
Genomic GenBank:BX323874 256605 bp Blast at MegaBLAST
Polypeptide UniProtKB:A6Y956 (1) 115 aa
Sequence Clusters UniGene:141624 (1)
Sequence Information (all 10)
OTHER tyrobp GENE PAGES
  • Gene:100101461 (1)
  • VEGA:OTTDARG00000027672 (1)
  • Ensembl(Zv9):ENSDARG00000094894 (1)
  • MAPPING INFORMATION
    Chr: 16 Details
    ORTHOLOGY
      Evidence
    Species Symbol Chromosome (Position) Accession # AA
    Zebrafish tyrobp 16  
    Human TYROBP 19 (19q13.1)
  • OMIM:604142
  • Gene:7305
  • Mouse Tyrobp 7 ( 17.45 cM)
  • MGI:1277211
  • Gene:22177
  • CITATIONS (8)