Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-061130-2
Gene Name: TYRO protein tyrosine kinase binding protein
Gene Symbol: tyrobp
Previous Name: dap12 (1)
Location: Chr: 16   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
  intestine, kidney, liver, lymphocyte (all 6) expand
MUTANTS AND TARGETED KNOCKDOWNS No data available
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Nasu-Hakola disease 221770
GENE ONTOLOGY
Ontology GO Term
Biological Process phosphatidylinositol 3-kinase signaling (more)
Cellular Component intracellular (more)
Molecular Function protein binding (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR026200 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA tyrobp-001 (1) 796
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM tyrobp No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    tyrobp Contained in: [BAC] DKEY-29H14, DKEY-104N21
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001100103 (1) 798 bp
    Genomic GenBank:BX323874 256605 bp Blast at MegaBLAST
    Polypeptide UniProtKB:A6Y956 (1) 115 aa
    Sequence Clusters UniGene:141624 (1)
    Sequence Information (all 10)
    OTHER tyrobp GENE PAGES
  • Gene:100101461 (1)
  • VEGA:OTTDARG00000027672 (1)
  • Ensembl(Zv9):ENSDARG00000094894 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA
    Zebrafish tyrobp 16  
    Human TYROBP 19 (19q13.1)
  • OMIM:604142
  • Gene:7305
  • Mouse Tyrobp 7 ( 17.45 cM)
  • MGI:1277211
  • Gene:22177
  • Orthology Details
    CITATIONS (8)