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ZIRC
ZFIN ID: ZDB-GENE-061128-2
Gene Name: aldehyde dehydrogenase 1 family, member A3
Gene Symbol: aldh1a3    Nomenclature History

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Previous Name: Raldh3 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have aldehyde dehydrogenase (NAD+) activity. Predicted to be involved in oxidation-reduction process. Human ortholog(s) of this gene implicated in isolated microphthalmia 8. Is expressed in several structures, including brain; immature eye; otic vesicle; pleuroperitoneal region; and sensory system. Orthologous to human ALDH1A3 (aldehyde dehydrogenase 1 family member A3).
Genome Resources: Alliance (1),  Gene:751785 (1),  Ensembl(GRCz11):ENSDARG00000076933 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa118 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa15721 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34007 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-aldh1a3 N/A 6
    PHENOTYPE
    Data: 8 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH aldh1a3 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    isolated microphthalmia 8 Alliance Microphthalmia, isolated 8 615113
    DISEASE ASSOCIATED WITH aldh1a3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process oxidation-reduction process (more)
    Molecular Function oxidoreductase activity (more)
    GO Terms (all 4)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA aldh1a3-201 (1)    Ensembl 2256
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM aldh1a3 No data available
    MARKER RELATIONSHIPS No data available
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001044745 (1) 1892 bp
    Genomic GenBank:CABZ01067605 (1) 52882 bp
    Select Tool
    Polypeptide UniProtKB:Q0H2G3 (1) 513 aa
    Sequence Clusters UniGene:83624 (1)
    Sequence Information (all 19)
    ORTHOLOGY for aldh1a3 ( Chr: 7 )
    CITATIONS (55)