ZFIN ID: ZDB-GENE-061128-2 |
Gene Name: | aldehyde dehydrogenase 1 family, member A3 | ||||||
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Gene Symbol: | aldh1a3 Nomenclature History | ||||||
Previous Name: | Raldh3 (1) | ||||||
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Gene Type: | protein_coding_gene | ||||||
Location: | Chr: 7 Mapping Details/Browsers | ||||||
Description: | Predicted to have aldehyde dehydrogenase (NAD+) activity. Predicted to be involved in oxidation-reduction process. Human ortholog(s) of this gene implicated in isolated microphthalmia 8. Is expressed in several structures, including brain; immature eye; otic vesicle; pleuroperitoneal region; and sensory system. Orthologous to human ALDH1A3 (aldehyde dehydrogenase 1 family member A3). | ||||||
Genome Resources: | Alliance (1), Gene:751785 (1), Ensembl(GRCz11):ENSDARG00000076933 (2) |
All Expression Data: | 20 figures from 16 publications |
Wild-type Stages, Structures: | Cleavage:64-cell (2.0h-2.25h) to Adult (90d-730d, breeding adult) |
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Allele | Type | Localization | Consequence | Mutagen | Suppliers |
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sa118 | Point Mutation | Unknown | Premature Stop | ENU |
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sa15721 | Point Mutation | Unknown | Premature Stop | ENU |
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sa34007 | Point Mutation | Unknown | Premature Stop | ENU |
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Targeting Reagent | Created Alleles | Publications |
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MO1-aldh1a3 | N/A | 6 |
Data: | 8 figures from 2 publications |
Observed in: |
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
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isolated microphthalmia 8 | Alliance | Microphthalmia, isolated 8 | 615113 |
Ontology | GO Term |
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Biological Process | oxidation-reduction process (more) |
Molecular Function | oxidoreductase activity (more) |
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Type | Name | Length (nt) | Analysis | |
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mRNA |
aldh1a3-201
(1)
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2256 |
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Browsers: UCSC, NCBI, Ensembl, ZFIN |
Type | Accession # | Length (bp/aa) | Analysis |
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RNA | RefSeq:NM_001044745 (1) | 1892 bp |
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Genomic | GenBank:CABZ01067605 (1) | 52882 bp | |
Polypeptide | UniProtKB:Q0H2G3 (1) | 513 aa |
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Sequence Clusters | UniGene:83624 (1) |