Gene
smcr8b
- ID
- ZDB-GENE-061122-1
- Name
- Smith-Magenis syndrome chromosome region, candidate 8b
- Symbol
- smcr8b Nomenclature History
- Previous Names
-
- smcr8
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to contribute to Rab guanyl-nucleotide exchange factor activity. Predicted to be involved in negative regulation of gene expression; regulation of TOR signaling; and regulation of macroautophagy. Predicted to colocalize with Atg1/ULK1 kinase complex. Orthologous to human SMCR8 (SMCR8-C9orf72 complex subunit).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Liu et al., 2022
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Folliculin/SMCR8, longin domain | Folliculin/SMCR8, tripartite DENN domain |
|---|---|---|---|
|
UniProtKB:Q6PUR7
|
985 | ||
|
UniProtKB:B3DGB6
|
985 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
smcr8b-201
(1)
|
Havana | 3662 nt |
Interactions and Pathways
No data available
Plasmids
No data available