ZFIN ID: ZDB-GENE-061111-1
Gene Name: syndecan 4
Gene Symbol: sdc4    Nomenclature History

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Previous Names: sdc4l, syn4 (1), wu:fc47g09

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Exhibits phosphatidylinositol-4,5-bisphosphate binding activity. Involved in several processes, including cell adhesion mediated by integrin; epiboly involved in gastrulation with mouth forming second; and stress fiber assembly. Localizes to focal adhesion. Is expressed in brain; neural crest; posterior lateral line primordium; and prechordal plate. Orthologous to human SDC4 (syndecan 4).
Genome Resources: Alliance (1),  Gene:568593 (1),  Ensembl(GRCz11):ENSDARG00000059906 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb257 Small Deletion Exon 2 Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • la025660Tg Transgenic Insertion Unknown Unknown DNA
    sa20823 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-sdc4 1
    MO1-sdc4 N/A 1
    MO2-sdc4 N/A 1
    MO3-sdc4 N/A 2
    MO4-sdc4 N/A 1
    MO5-sdc4 N/A 1
    DISEASE ASSOCIATED WITH sdc4 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH sdc4 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell adhesion (more)
    Cellular Component focal adhesion (more)
    Molecular Function phosphatidylinositol-4,5-bisphosphate binding (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA sdc4-201 (1)    Ensembl 2306
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM sdc4 No data available
    MARKER RELATIONSHIPS
    sdc4 Contained in: [BAC] CH73-166O16 (1), CH211-8I17 (1)
    sdc4 Encodes: [EST] fc47g09
    [STS] chunp30591
    [cDNA] MGC:162342 (1), MGC:174221 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001048149 (1) 944 nt
    Genomic GenBank:AL954861 (1) 175026 nt
    Select Tool
    Polypeptide UniProtKB:Q08BE1 (1) 258 aa
    Sequence Information (all 24)
    ORTHOLOGY for sdc4 ( Chr: 6 )
    CITATIONS (41)