Gene

papss2a

ID
ZDB-GENE-061110-85
Name
3'-phosphoadenosine 5'-phosphosulfate synthase 2a
Symbol
papss2a Nomenclature History
Previous Names
  • zgc:153748
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Predicted to have ATP binding activity; adenylylsulfate kinase activity; and sulfate adenylyltransferase (ATP) activity. Predicted to be involved in 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process and sulfate assimilation. Human ortholog(s) of this gene implicated in spondyloepimetaphyseal dysplasia, Pakistani type. Orthologous to human PAPSS2 (3'-phosphoadenosine 5'-phosphosulfate synthase 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Gonzalez et al., 2017
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With papss2a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
spondyloepimetaphyseal dysplasia, Pakistani type Alliance Brachyolmia 4 with mild epiphyseal and metaphyseal changes 612847
Associated With papss2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002650 Sulphate adenylyltransferase
Domain IPR024951 Sulphate adenylyltransferase catalytic domain
Domain IPR025980 ATP-sulfurylase PUA-like domain
Family IPR002891 Adenylyl-sulfate kinase
Homologous_superfamily IPR014729 Rossmann-like alpha/beta/alpha sandwich fold
Homologous_superfamily IPR015947 PUA-like superfamily
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length Adenylyl-sulfate kinase ATP-sulfurylase PUA-like domain P-loop containing nucleoside triphosphate hydrolase PUA-like superfamily Rossmann-like alpha/beta/alpha sandwich fold Sulphate adenylyltransferase Sulphate adenylyltransferase catalytic domain
UniProtKB:A0JPF3 612
UniProtKB:F1QFG2 612
UniProtKB:A0A2R8RUC9 613
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations