ZFIN ID: ZDB-GENE-061110-135
Gene Name: aspartyl-tRNA synthetase 1
Gene Symbol: dars1    Nomenclature History

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Previous Names: dars, wu:fc17a11, zgc:154056

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have RNA binding activity and aspartate-tRNA ligase activity. Predicted to be involved in aspartyl-tRNA aminoacylation. Predicted to localize to aminoacyl-tRNA synthetase multienzyme complex and cytosol. Orthologous to human DARS1 (aspartyl-tRNA synthetase 1).
Genome Resources: Alliance (1),  Gene:324025 (1),  Ensembl(GRCz11):ENSDARG00000070043 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la026716Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-dars1
    1
    CRISPR2-dars1
    1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH dars1 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Hypomyelination with brainstem and spinal cord involvement and leg spasticity 615281
    DISEASE ASSOCIATED WITH dars1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process aspartyl-tRNA aminoacylation (more)
    Cellular Component cytoplasm (more)
    Molecular Function aminoacyl-tRNA ligase activity (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dars1 No data available
    MARKER RELATIONSHIPS
    dars1 Encodes: [EST] fc17a11
    [cDNA] MGC:154056 (1), MGC:173454 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001077611 (1)
    Genomic GenBank:CU694482 (1) 35104 nt
    Select Tool
    Polypeptide UniProtKB:A0AUR8 (1) 531 aa
    Sequence Information (all 22)
    ORTHOLOGY for dars1 ( Chr: 9 )
    CITATIONS (22)