ZFIN ID: ZDB-GENE-061110-106
Gene Name: zinc finger DHHC-type palmitoyltransferase 15b
Gene Symbol: zdhhc15b    Nomenclature History

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Previous Names: zdhhc15, fc02b12, wu:fc02b12, zgc:152683

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 14 Mapping Details/Browsers
Description: Exhibits protein-cysteine S-palmitoyltransferase activity and zinc ion binding activity. Involved in nervous system development and protein lipidation. Localizes to the integral component of Golgi membrane. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability. Is expressed in diencephalon; forebrain; head; midbrain; and telencephalon. Orthologous to human ZDHHC15 (zinc finger DHHC-type containing 15).
Genome Resources: Alliance (1),  Gene:777734 (1),  Ensembl(GRCz11):ENSDARG00000071872 (2)
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Wild-type Stages, Structures: Cleavage:8-cell (1.25h-1.5h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la027490Tg Transgenic Insertion Unknown Unknown DNA
sa10212 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35646 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-zdhhc15b N/A 1
    DISEASE ASSOCIATED WITH zdhhc15b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH zdhhc15b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process peptidyl-L-cysteine S-palmitoylation (more)
    Cellular Component integral component of Golgi membrane (more)
    Molecular Function protein-cysteine S-palmitoyltransferase activity (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR001594 Palmitoyltransferase, DHHC domain
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA zdhhc15b-201 (1)    Ensembl 2565
    ncRNA zdhhc15b-002 (1)    Ensembl 2744
    zdhhc15b-003 (1)    Ensembl 631
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM zdhhc15b No data available
    MARKER RELATIONSHIPS
    zdhhc15b Contained in: [BAC] DKEY-286D7 (1) (order this)
    zdhhc15b Encodes: [EST] fc02b12
    [cDNA] MGC:152683 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001077781 (1) 2566 bp
    Genomic GenBank:CR812849 (1) 102223 bp
    Select Tool
    Polypeptide UniProtKB:A0JMB1 (1) 332 aa
    Sequence Information (all 16)
    ORTHOLOGY for zdhhc15b ( Chr: 14 )
    CITATIONS (28)