Gene

nkd1

ID
ZDB-GENE-061108-3
Name
NKD inhibitor of WNT signaling pathway 1
Symbol
nkd1 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have calcium ion binding activity. Involved in several processes, including Kupffer's vesicle development; embryonic heart tube development; and negative regulation of protein import into nucleus. Localizes to cytoplasm and plasma membrane. Is expressed in several structures, including forerunner cell group; hindbrain neural rod; mesoderm; neural tube; and tail bud. Orthologous to human NKD1 (NKD inhibitor of WNT signaling pathway 1).
Genome Resources
Note
None
Expression
All Expression Data
4 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nkd1 Human Ortholog
No data available
Associated With nkd1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR018247 EF-Hand 1, calcium-binding site
Domain IPR002048 EF-hand domain
Family IPR040140 Protein naked cuticle-like
Homologous_superfamily IPR011992 EF-hand domain pair
Domain Details Per Protein
Protein Length EF-Hand 1, calcium-binding site EF-hand domain EF-hand domain pair Protein naked cuticle-like
UniProtKB:B0S7E2 440
UniProtKB:Q2TJA6 440
UniProtKB:A0A1I7Q3W8 439
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations