ZFIN ID: ZDB-GENE-061103-493
Gene Name: C-terminal Src kinase
Gene Symbol: csk    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name: zgc:154049

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 25 Mapping Details/Browsers
Description: Predicted to have ATP binding activity and non-membrane spanning protein tyrosine kinase activity. Involved in convergent extension involved in gastrulation. Orthologous to human CSK (C-terminal Src kinase).
Genome Resources: Alliance (1),  Gene:556454 (1),  Ensembl(GRCz11):ENSDARG00000067996 (2)
GENE EXPRESSION
All Expression Data: Fig. 1 from Jopling et al., 2007
Wild-type Stages, Structures: Cleavage:8-cell (1.25h-1.5h) to Segmentation:14-19 somites (16.0h-19.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa32531 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-csk N/A 1
    DISEASE ASSOCIATED WITH csk HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH csk VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process convergent extension involved in gastrulation (more)
    Molecular Function ATP binding (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA csk-201 (1)    Ensembl 2944
    csk-202 (1)    Ensembl 561
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM csk No data available
    MARKER RELATIONSHIPS
    csk Contained in: [BAC] DKEY-88P16 (1) (order this), DKEYP-77B4 (1)
    csk Encodes: [cDNA] MGC:154049 (1), MGC:192674 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001077599 (1) 2844 nt
    Genomic GenBank:CR846093 (1) 214328 nt Blast at MegaBLAST
    Polypeptide UniProtKB:A0JMN4 (1) 450 aa
    Sequence Information (all 14)
    ORTHOLOGY for csk ( Chr: 25 )
    CITATIONS (24)