ZFIN ID: ZDB-GENE-061103-277
Gene Name: speckle type BTB/POZ protein like b
Gene Symbol: spoplb    Nomenclature History

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Previous Names: im:6961637, zgc:153365

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Predicted to have ubiquitin protein ligase binding activity. Predicted to be involved in negative regulation of protein ubiquitination; proteasome-mediated ubiquitin-dependent protein catabolic process; and regulation of proteolysis. Predicted to localize to the Cul3-RING ubiquitin ligase complex; cytoplasm; and nucleus. Orthologous to human SPOPL (speckle type BTB/POZ protein like).
Genome Resources: Alliance (1),  Gene:558170 (1), 
GENE EXPRESSION
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH spoplb HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH spoplb VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process negative regulation of protein ubiquitination (more)
Cellular Component Cul3-RING ubiquitin ligase complex (more)
Molecular Function ubiquitin protein ligase binding (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR000210 BTB/POZ domain
Domain IPR002083 MATH/TRAF domain
Homologous_superfamily IPR008974 TRAF-like
Homologous_superfamily IPR011333 SKP1/BTB/POZ domain superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA spoplb-202 (1)    Ensembl 2473
ncRNA spoplb-002 (1) 485
Browsers: NCBI
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM spoplb No data available
MARKER RELATIONSHIPS
spoplb Contained in: [BAC] CH211-227N13 (1)
spoplb Encodes: [EST] IMAGE:6961637
[cDNA] MGC:153365 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001079969 (1) 2377 bp
Genomic GenBank:BX323597 (1) 177773 bp
Select Tool
Polypeptide UniProtKB:A0JMG1 (1) 392 aa
Sequence Information (all 10)
ORTHOLOGY for spoplb ( Chr: 11 )
CITATIONS (18)