ZFIN ID: ZDB-GENE-061103-253
Gene Name: regulatory factor X, 3 (influences HLA class II expression)
Gene Symbol: rfx3    Nomenclature History

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Previous Name: zgc:153245 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including cilium-dependent cell motility; epithelial cilium movement involved in determination of left/right asymmetry; and regulation of insulin secretion. Predicted to localize to nucleus. Orthologous to human RFX3 (regulatory factor X3).
Genome Resources: Alliance (1),  Gene:570989 (1),  Ensembl(GRCz11):ENSDARG00000014550 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa16866 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17373 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31758 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-rfx3
    1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH rfx3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH rfx3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cilium-dependent cell motility (more)
    Cellular Component nucleus (more)
    Molecular Function transcription regulatory region sequence-specific DNA binding (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA rfx3-001 (1) 1822
    rfx3-002 (1) 1153
    Browsers: NCBI
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM rfx3 No data available
    MARKER RELATIONSHIPS
    rfx3 Contained in: [BAC] CH73-59D19 (1), CH73-263E18 (1)
    rfx3 Encodes: [cDNA] MGC:153245 (1), MGC:192751 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001080048 (1) 2798 nt
    Genomic GenBank:CU468737 (1) 89905 nt
    Select Tool
    Polypeptide UniProtKB:A0JMF8 (1) 765 aa
    Sequence Information (all 19)
    ORTHOLOGY for rfx3 ( Chr: 10 )
    CITATIONS (24)