rfx3

ID

ZDB-GENE-061103-253

Name

regulatory factor X, 3 (influences HLA class II expression)

Symbol

rfx3 Nomenclature History

Previous Names

zgc:153245 (1)

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including cilium-dependent cell motility; epithelial cilium movement involved in determination of left/right asymmetry; and regulation of insulin secretion. Predicted to act upstream of or within cell differentiation. Predicted to be located in nucleus. Orthologous to human RFX3 (regulatory factor X3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rfx3 Human Ortholog

No data available

Associated With rfx3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003150	DNA-binding RFX-type winged-helix domain
Domain	IPR007668	RFX1 transcription activation region
Family	IPR039779	RFX-like DNA-binding protein
Homologous_superfamily	IPR036388	Winged helix-like DNA-binding domain superfamily
Homologous_superfamily	IPR036390	Winged helix DNA-binding domain superfamily