Gene
rfx3
- ID
- ZDB-GENE-061103-253
- Name
- regulatory factor X, 3 (influences HLA class II expression)
- Symbol
- rfx3 Nomenclature History
- Previous Names
-
- zgc:153245 (1)
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including cilium-dependent cell motility; epithelial cilium movement involved in determination of left/right asymmetry; and regulation of insulin secretion. Predicted to localize to nucleus. Orthologous to human RFX3 (regulatory factor X3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003150 | DNA-binding RFX-type winged-helix domain |
| Domain | IPR007668 | RFX1 transcription activation region |
| Family | IPR039779 | RFX-like DNA-binding protein |
| Homologous_superfamily | IPR036388 | Winged helix-like DNA-binding domain superfamily |
| Homologous_superfamily | IPR036390 | Winged helix DNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | DNA-binding RFX-type winged-helix domain | RFX1 transcription activation region | RFX-like DNA-binding protein | Winged helix DNA-binding domain superfamily | Winged helix-like DNA-binding domain superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PTM1
|
740 | |||||
|
UniProtKB:A0JMF8
|
765 | |||||
|
UniProtKB:B2GSV8
|
765 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available