ZFIN ID: ZDB-GENE-061103-196
Gene Name: chloride channel 7
Gene Symbol: clcn7
Sequence Ontology ID : SO:0000704

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Previous Names: im:7155923, zgc:153490 (1)

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(Including Attributions)
Location: Chr: 3 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have voltage-gated chloride channel activity; predicted to be involved in chloride transmembrane transport and response to pH; predicted to localize to the cytoplasmic vesicle and  ...
GENE EXPRESSION
All Expression Data: 8 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7155923]
  6 figures (5 images) from Thisse et al., 2004 [IMAGE:7154411]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa2122 Point Mutation Unknown Splice Site ENU
sa14513 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa20020 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40074 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40075 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45140 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH clcn7 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    autosomal dominant osteopetrosis 2 Osteopetrosis, autosomal dominant 2 166600
    autosomal recessive osteopetrosis 4 Osteopetrosis, autosomal recessive 4 611490
    DISEASE ASSOCIATED WITH clcn7 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process chloride transport (more)
    Cellular Component integral component of membrane (more)
    Molecular Function voltage-gated chloride channel activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000644 (1)
  • InterPro:IPR001807 (1)
  • InterPro:IPR002249 (1)
  • InterPro:IPR014743 (1)
  • PROSITE:PS51371 (1)
  • Pfam:PF00571 (1)
  • Pfam:PF00654 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA clcn7-001 (1) 3971
    ncRNA clcn7-002 (1) 826
    clcn7-003 (1) 853
    clcn7-004 (1) 572
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM clcn7 No data available
    MARKER RELATIONSHIPS
    clcn7Contained in: [BAC] CH211-157C3 (1) (order this)
    clcn7Encodes: [EST] IMAGE:7154411 (1) (order this), IMAGE:7155923 (1) (order this)
    [cDNA] MGC:153490 (1) (order this), MGC:193084 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001077537 (1) 3982bp
    Genomic GenBank:CR394572 (1) 147156bp
    Select Tool
    Polypeptide UniProtKB:A0JMG8 (1) 795aa
    Sequence Clusters UniGene:84256 (1)
    Sequence Information (all 22)
    OTHER clcn7 GENE PAGES
  • Alliance (1)
  • Gene:553351 (1)
  • VEGA:OTTDARG00000028016 (1)
  • Ensembl(GRCz11):ENSDARG00000019556 (2)
  • ORTHOLOGY for clcn7 (Chr: 3)
    CITATIONS (23)