Gene

sfrp1b

ID
ZDB-GENE-061103-1
Name
secreted frizzled-related protein 1b
Symbol
sfrp1b Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to have Wnt-protein binding activity. Predicted to be involved in canonical Wnt signaling pathway; negative regulation of canonical Wnt signaling pathway; and non-canonical Wnt signaling pathway. Predicted to localize to extracellular space. Is expressed in several structures, including endoderm; pronephric duct; tail bud; yolk; and yolk syncytial layer. Orthologous to human SFRP1 (secreted frizzled related protein 1).
Genome Resources
Note
None
Expression
All Expression Data
6 figures from 4 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sfrp1b Human Ortholog
No data available
Associated With sfrp1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001134 Netrin domain
Domain IPR018933 Netrin module, non-TIMP type
Domain IPR020067 Frizzled domain
Domain IPR041760 SFRP1, cysteine-rich domain
Family IPR015526 Frizzled/secreted frizzled-related protein
Family IPR026559 Secreted frizzled-related protein 1
Homologous_superfamily IPR008993 Tissue inhibitor of metalloproteinases-like, OB-fold
Homologous_superfamily IPR036790 Frizzled cysteine-rich domain superfamily
Domain Details Per Protein
Protein Length Frizzled cysteine-rich domain superfamily Frizzled domain Frizzled/secreted frizzled-related protein Netrin domain Netrin module, non-TIMP type Secreted frizzled-related protein 1 SFRP1, cysteine-rich domain Tissue inhibitor of metalloproteinases-like, OB-fold
UniProtKB:A3KNP6 300
UniProtKB:A8KBU5 300
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations