ZFIN ID: ZDB-GENE-061027-60
Gene Name: ATPase plasma membrane Ca2+ transporting 4
Gene Symbol: atp2b4    Nomenclature History

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Previous Names: pmca4 (1), zgc:152801

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Predicted to have PDZ domain binding activity and calcium transmembrane transporter activity, phosphorylative mechanism. Predicted to be involved in regulation of cytosolic calcium ion concentration. Predicted to localize to the integral component of membrane. Is expressed in several structures, including blood; eye; gill; liver; and pleuroperitoneal region. Orthologous to human ATP2B4 (ATPase plasma membrane Ca2+ transporting 4).
Genome Resources: Alliance (1),  Gene:768304 (1),  Ensembl(GRCz11):ENSDARG00000044902 (1)
GENE EXPRESSION
All Expression Data: Fig. 5 from Liao et al., 2007
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la010065Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la017760Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa6208 Point Mutation Unknown Premature Stop ENU
    sa10432 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21897 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH atp2b4 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH atp2b4 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process calcium ion transmembrane transport (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ATP binding (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Family IPR001757 P-type ATPase
    Domain IPR004014 Cation-transporting P-type ATPase, N-terminal
    Domain IPR006068 Cation-transporting P-type ATPase, C-terminal
    Family IPR006408 P-type ATPase, subfamily IIB
    Homologous_superfamily IPR008250 P-type ATPase, A domain superfamily
    PTM IPR018303 P-type ATPase, phosphorylation site
    Domain IPR022141 Plasma membrane calcium transporting P-type ATPase, C-terminal
    Homologous_superfamily IPR023214 HAD superfamily
    Homologous_superfamily IPR023298 P-type ATPase, transmembrane domain superfamily
    Homologous_superfamily IPR023299 P-type ATPase, cytoplasmic domain N
    Family IPR034304 Plasma membrane calcium-transporting ATPase 4
    Homologous_superfamily IPR036412 HAD-like superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA atp2b2-202 (1)    Ensembl 10382
    atp2b2-204 (1)    Ensembl 1024
    ncRNA atp2b4-002 (1)    Ensembl 1976
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM atp2b4 No data available
    MARKER RELATIONSHIPS
    atp2b4 Contained in: [BAC] CH211-195N8 (1)
    atp2b4 Encodes: [cDNA] MGC:152801 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001077467 (1) 1981 bp
    Genomic GenBank:BX545854 (1) 190179 bp
    Select Tool
    Polypeptide UniProtKB:A0A2R8QLX3 (1) 1197 aa
    Sequence Information (all 22)
    ORTHOLOGY for atp2b4 ( Chr: 11 )
    CITATIONS (28)