ZFIN ID: ZDB-GENE-061027-393
Gene Name: myosin heavy chain 7-like
Gene Symbol: myh7l    Nomenclature History

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Previous Names: myh1 (1), vmhcl, zgc:113832, zgc:152732

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have ATP binding activity; actin filament binding activity; and motor activity. Predicted to localize to the myosin complex. Human ortholog(s) of this gene implicated in cardiomyopathy (multiple); congenital heart disease (multiple); distal myopathy 1; heart conduction disease (multiple); and hyaline body myopathy (multiple). Is expressed in adaxial cell; cardiovascular system; and myotome. Orthologous to human MYH6 (myosin heavy chain 6) and MYH7 (myosin heavy chain 7).
Genome Resources: Alliance (1),  Gene:768300 (1),  Ensembl(GRCz11):ENSDARG00000079782 (2)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH myh7l HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH myh7l VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Cellular Component myosin complex (more)
Molecular Function actin binding (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Binding_site IPR000048 IQ motif, EF-hand binding site
Domain IPR001609 Myosin head, motor domain
Domain IPR002928 Myosin tail
Domain IPR004009 Myosin, N-terminal, SH3-like
Homologous_superfamily IPR008989 Myosin S1 fragment, N-terminal
Homologous_superfamily IPR027401 Myosin IQ motif-containing domain superfamily
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036961 Kinesin motor domain superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
aberrant processed transcript myh7l-207 (1)    Ensembl 661
mRNA myh7l-201 (1)    Ensembl 826
myh7l-203 (1)    Ensembl 6016
myh7l-205 (1)    Ensembl 686
ncRNA vmhcl-003 (1)    Ensembl 795
vmhcl-006 (1)    Ensembl 460
vmhcl-007 (1)    Ensembl 579
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM myh7l
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
Tg(myh7l:LOXP-MYC-BFP-STOP-LOXP-NTR-mCherry) myh7l BFPLOXPmCherryMYCNTR Danio rerio 1 4
MARKER RELATIONSHIPS
myh7l Contained in: [BAC] DKEY-77A20 (1) (order this)
myh7l Encodes: [cDNA] MGC:113832 (1), MGC:152732 (1), MGC:192541 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001077464 (1) 6068 bp
Genomic GenBank:CR925708 (1) 229824 bp Blast at MegaBLAST
Polypeptide UniProtKB:A0A2R8QM44 (1) 1963 aa
Sequence Information (all 38)
ORTHOLOGY for myh7l ( Chr: 2 )
CITATIONS (31)