Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-061019-2
Gene Name: Fas cell surface death receptor
Gene Symbol: fas
Location: Chr: 17   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: Fig. 1 from Choi et al., 2007
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Gastrula:50%-epiboly (5.25h-5.66h)
  blastoderm
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: sa11234
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Autoimmune lymphoproliferative syndrome, type IA 601859
Squamous cell carcinoma, burn scar-related, somatic
{Autoimmune lymphoproliferative syndrome} 601859
GENE ONTOLOGY
Ontology GO Term
Biological Process positive regulation of apoptotic process (more)
Cellular Component membrane (more)
Molecular Function transmembrane signaling receptor activity (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000488 (1)
  • InterPro:IPR001368 (1)
  • InterPro:IPR008063 (1)
  • InterPro:IPR011029 (1)
  • PROSITE:PS50017 (1)
  • PROSITE:PS50050 (1)
  • Pfam:PF00020 (1)
  • Pfam:PF00531 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA fas-001 (1) 984
    ncRNA fas-002 (1) 732
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM fas No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    fas Contained in: [BAC] DKEY-116M16 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_685355 (1) 979 bp
    Genomic GenBank:CU464131 (1) 43637 bp
    Select Tool
    Polypeptide UniProtKB:F1QG24 (1) 293 aa
    Sequence Clusters UniGene:150815 (1)
    Sequence Information (all 8)
    OTHER fas GENE PAGES
  • Gene:768248 (1)
  • VEGA:OTTDARG00000035055 (1)
  • Ensembl(Zv9):ENSDARG00000043586 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish fas 17  
    Human FAS 10 (10q24.1)
  • OMIM:134637
  • Gene:355
  • Orthology Details
    CITATIONS (16)