ZFIN ID: ZDB-GENE-061019-2
Gene Name: Fas cell surface death receptor
Gene Symbol: fas
Location: Chr: 17   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Cleavage:16-cell (1.5h-1.75h) to Adult (90d-730d, breeding adult)
  blastoderm, brain, eye, gut (all 7) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Knockdown reagents: MO1-fas (1), MO2-fas (1)

Allele Type Mutagen Suppliers
sa11234 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • PHENOTYPE
    Data: Fig. 2 from Ferrari et al., 2014
    Observed in: head, notochord, pericardium, post-vent region
    DISEASE ASSOCIATED WITH fas HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    autoimmune lymphoproliferative syndrome Autoimmune lymphoproliferative syndrome, type IA 601859
    {Autoimmune lymphoproliferative syndrome} 601859
    Squamous cell carcinoma, burn scar-related, somatic
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of apoptotic process (more)
    Cellular Component membrane (more)
    Molecular Function transmembrane signaling receptor activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000488 (1)
  • InterPro:IPR001368 (1)
  • InterPro:IPR008063 (1)
  • InterPro:IPR011029 (1)
  • PROSITE:PS50017 (1)
  • PROSITE:PS50050 (1)
  • Pfam:PF00020 (1)
  • Pfam:PF00531 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA fas-001 (1) 984
    ncRNA fas-002 (1) 732
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM fas No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    fas Contained in: [BAC] DKEY-116M16 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_685355 (1) 988 bp
    Genomic GenBank:CU464131 (1) 43637 bp
    Select Tool
    Polypeptide UniProtKB:F1QG24 (1) 293 aa
    Sequence Clusters UniGene:150815 (1)
    Sequence Information (all 8)
    OTHER fas GENE PAGES
  • Gene:768248 (1)
  • VEGA:OTTDARG00000035055 (1)
  • Ensembl(Zv9):ENSDARG00000043586 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish fas 17  
    Human FAS 10 (10q24.1)
  • OMIM:134637
  • Gene:355
  • Orthology Details
    CITATIONS (17)