ZFIN ID: ZDB-GENE-061019-2
Gene Name: Fas cell surface death receptor
Gene Symbol: fas

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(Including Attributions)
Location: Chr: 17 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Cleavage:16-cell (1.5h-1.75h) to Adult (90d-730d, breeding adult)
  blastoderm, brain, eye, gut (all 7) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa11234 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: MO1-fas (1), MO2-fas (1)
    PHENOTYPE
    Data: Fig. 2 from Ferrari et al., 2014
    Observed in: head, notochord, pericardium, post-vent region
    DISEASE ASSOCIATED WITH fas HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    autoimmune lymphoproliferative syndrome Autoimmune lymphoproliferative syndrome, type IA 601859
    {Autoimmune lymphoproliferative syndrome} 601859
    Squamous cell carcinoma, burn scar-related, somatic
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of apoptotic process (more)
    Cellular Component integral component of membrane (more)
    Molecular Function transmembrane signaling receptor activity (more)
    GO Terms (all 15)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000488 (1)
  • InterPro:IPR001368 (1)
  • InterPro:IPR008063 (1)
  • InterPro:IPR011029 (1)
  • InterPro:IPR033998 (1)
  • InterPro:IPR034055 (1)
  • PROSITE:PS50017 (1)
  • PROSITE:PS50050 (1)
  • Pfam:PF00020 (1)
  • Pfam:PF00531 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA fas-001 (1) 984
    ncRNA fas-002 (1) 732
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM fas No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    fasContained in: [BAC] DKEY-116M16 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_685355 (1) 987bp
    Genomic GenBank:CU464131 (1) 43637bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4ICQ7 (1) 306aa
    Sequence Clusters UniGene:150815 (1)
    Sequence Information (all 10)
    OTHER fas GENE PAGES
  • Gene:768248 (1)
  • VEGA:OTTDARG00000035055 (1)
  • Ensembl(GRCz10):ENSDARG00000043586 (1)
  • ORTHOLOGY for fas (Chr: 17)
    CITATIONS (21)