Gene

atp2b2

ID
ZDB-GENE-061016-1
Name
ATPase plasma membrane Ca2+ transporting 2
Symbol
atp2b2 Nomenclature History
Previous Names
  • pmca2 (1)
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have PDZ domain binding activity and calcium transmembrane transporter activity, phosphorylative mechanism. Predicted to be involved in neuron differentiation and regulation of cytosolic calcium ion concentration. Predicted to localize to several cellular components, including integral component of plasma membrane; intracellular membrane-bounded organelle; and postsynaptic density membrane. Is expressed in several structures, including blood; eye; heart; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 12. Orthologous to human ATP2B2 (ATPase plasma membrane Ca2+ transporting 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
11 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With atp2b2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive nonsyndromic deafness 12 Alliance {Deafness, autosomal recessive 12, modifier of} 601386
Associated With atp2b2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004014 Cation-transporting P-type ATPase, N-terminal
Domain IPR006068 Cation-transporting P-type ATPase, C-terminal
Domain IPR022141 Plasma membrane calcium transporting P-type ATPase, C-terminal
Family IPR001757 P-type ATPase
Family IPR006408 P-type ATPase, subfamily IIB
Family IPR030322 Plasma membrane calcium-transporting ATPase 2
Homologous_superfamily IPR008250 P-type ATPase, A domain superfamily
Homologous_superfamily IPR023214 HAD superfamily
Homologous_superfamily IPR023298 P-type ATPase, transmembrane domain superfamily
Homologous_superfamily IPR023299 P-type ATPase, cytoplasmic domain N
Homologous_superfamily IPR036412 HAD-like superfamily
PTM IPR018303 P-type ATPase, phosphorylation site
Domain Details Per Protein
Protein Length Cation-transporting P-type ATPase, C-terminal Cation-transporting P-type ATPase, N-terminal HAD-like superfamily HAD superfamily Plasma membrane calcium-transporting ATPase 2 Plasma membrane calcium transporting P-type ATPase, C-terminal P-type ATPase P-type ATPase, A domain superfamily P-type ATPase, cytoplasmic domain N P-type ATPase, phosphorylation site P-type ATPase, subfamily IIB P-type ATPase, transmembrane domain superfamily
UniProtKB:F1RC03 1253
UniProtKB:B2CZB8 1253
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations