Gene

prkar2aa

ID
ZDB-GENE-030131-1007
Name
protein kinase, cAMP-dependent, regulatory, type II, alpha A
Symbol
prkar2aa Nomenclature History
Previous Names
  • wu:fb55f12
  • wu:fj29e12
  • wu:fj33e06
  • zgc:153742
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have 3',5'-cyclic-GMP phosphodiesterase activity. Predicted to be involved in cGMP-mediated signaling. Predicted to localize to cytosol. Human ortholog(s) of this gene implicated in congestive heart failure. Orthologous to human PRKAR2A (protein kinase cAMP-dependent type II regulatory subunit alpha).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With prkar2aa Human Ortholog
No data available
Associated With prkar2aa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018488 Cyclic nucleotide-binding, conserved site
Domain IPR000595 Cyclic nucleotide-binding domain
Domain IPR003117 cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain
Family IPR012198 cAMP-dependent protein kinase regulatory subunit
Homologous_superfamily IPR014710 RmlC-like jelly roll fold
Homologous_superfamily IPR018490 Cyclic nucleotide-binding-like
Domain Details Per Protein
Protein Length cAMP-dependent protein kinase regulatory subunit cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain Cyclic nucleotide-binding, conserved site Cyclic nucleotide-binding domain Cyclic nucleotide-binding-like RmlC-like jelly roll fold
UniProtKB:A9C3T0 397
UniProtKB:Q08BH1 397
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations