ZFIN ID: ZDB-GENE-061013-537
Gene Name: DnaJ heat shock protein family (Hsp40) member B2
Gene Symbol: dnajb2    Nomenclature History

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Previous Names: sb:eu730, zgc:153268

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Human ortholog(s) of this gene implicated in distal spinal muscular atrophy type 5. Orthologous to human DNAJB2 (DnaJ heat shock protein family (Hsp40) member B2).
Genome Resources: Alliance (1),  Gene:561686 (1),  Ensembl(GRCz11):ENSDARG00000058644 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2005 [eu730]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa17753 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41355 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-dnajb2 N/A 1
    MO2-dnajb2 N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH dnajb2 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    distal spinal muscular atrophy type 5 Alliance Spinal muscular atrophy, distal, autosomal recessive, 5 614881
    DISEASE ASSOCIATED WITH dnajb2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY No data available
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR001623 DnaJ domain
    Conserved_site IPR003903 Ubiquitin interacting motif
    Conserved_site IPR018253 DnaJ domain, conserved site
    Homologous_superfamily IPR036869 Chaperone J-domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dnajb2-201 (1)    Ensembl 2117
    dnajb2-202 (1)    Ensembl 745
    dnajb2-204 (1)    Ensembl 662
    ncRNA dnajb2-002 (1) 705
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dnajb2 No data available
    MARKER RELATIONSHIPS
    dnajb2 Contained in: [BAC] CH73-199E17 (1)
    dnajb2 Encodes: [EST] eu730 (1)
    [cDNA] MGC:153268 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001079993 (1) 2152 bp
    Genomic GenBank:CU639452 (1) 100865 bp
    Select Tool
    Polypeptide UniProtKB:F1R1B0 (1) 389 aa
    Sequence Information (all 15)
    ORTHOLOGY for dnajb2 ( Chr: 9 )
    CITATIONS (16)