ZFIN ID: ZDB-GENE-061013-438
Gene Name: malic enzyme 1, NADP(+)-dependent, cytosolic
Gene Symbol: me1    Nomenclature History

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Previous Name: zgc:153079

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to have malate dehydrogenase (decarboxylating) (NADP+) activity. Predicted to be involved in malate metabolic process and pyruvate metabolic process. Predicted to localize to mitochondrion. Orthologous to human ME1 (malic enzyme 1).
Genome Resources: Alliance (1),  Gene:768196 (1),  Ensembl(GRCz11):ENSDARG00000053215 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Larval:Day 4 (96.0h-120.0h) to Larval:Day 4 (96.0h-120.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la010366Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la011773Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39116 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH me1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH me1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process oxidation-reduction process (more)
    Cellular Component mitochondrion (more)
    Molecular Function malate dehydrogenase (decarboxylating) (NAD+) activity (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA me1-201 (1)    Ensembl 1956
    me1-202 (1)    Ensembl 1910
    ncRNA me1-003 (1)    Ensembl 782
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM me1 No data available
    MARKER RELATIONSHIPS
    me1 Contained in: [BAC] DKEY-66C10 (1) (order this), DKEY-83G2 (1) (order this), DKEY-165N16 (1) (order this)
    me1 Encodes: [cDNA] MGC:153079 (1), MGC:173461 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001077338 (1) 1922 nt
    Genomic GenBank:AL844887 (1) 243870 nt Blast at MegaBLAST
    Polypeptide UniProtKB:A0A286Y7Z2 (1) 607 aa
    Sequence Information (all 23)
    ORTHOLOGY for me1 ( Chr: 16 )
    CITATIONS (28)