Gene

eif2ak1

ID
ZDB-GENE-061013-268
Name
eukaryotic translation initiation factor 2-alpha kinase 1
Symbol
eif2ak1 Nomenclature History
Previous Names
  • fj97h09
  • wu:fj97h09
  • zgc:153232
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have protein kinase activity. Predicted to be involved in protein phosphorylation and translational initiation. Orthologous to human EIF2AK1 (eukaryotic translation initiation factor 2 alpha kinase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With eif2ak1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
?Leukoencephalopathy, motor delay, spasticity, and dysarthria syndrome 618878
Associated With eif2ak1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Domain Details Per Protein
Protein Length Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Serine/threonine-protein kinase, active site
UniProtKB:F1QQF6 621
UniProtKB:A0A2R8QP46 621
UniProtKB:Q08BM5 621
UniProtKB:F1Q5Z3 668
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations