ZFIN ID: ZDB-GENE-061013-249
Gene Name: interleukin 1 receptor accessory protein-like 1a
Gene Symbol: il1rapl1a    Nomenclature History

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Previous Names: fi18g04, wu:fi18g04, zgc:152866 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have NAD(P)+ nucleosidase activity; NAD+ nucleotidase, cyclic ADP-ribose generating; and interleukin-1 receptor activity. Predicted to be involved in negative regulation of exocytosis. Predicted to localize to cytoplasm; integral component of membrane; and plasma membrane. Is expressed in optic tectum and telencephalon. Human ortholog(s) of this gene implicated in intellectual disability and non-syndromic X-linked intellectual disability. Orthologous to human IL1RAPL1 (interleukin 1 receptor accessory protein like 1).
Genome Resources: Alliance (1),  Gene:568868 (1),  Ensembl(GRCz11):ENSDARG00000062045 (1)
GENE EXPRESSION
All Expression Data: Fig. 1 from Yoshida et al., 2008
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Days 7-13 (168.0h-14d, 4.5mm, 8 teeth)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la026888Tg Transgenic Insertion Unknown Unknown DNA
sa2524 Point Mutation Unknown Premature Stop ENU
sa5821 Point Mutation Unknown Premature Stop ENU
sa12814 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13024 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa15551 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21502 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34666 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34667 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34668 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41443 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH il1rapl1a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    non-syndromic X-linked intellectual disability Alliance Mental retardation, X-linked 21/34 300143
    DISEASE ASSOCIATED WITH il1rapl1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process signal transduction (more)
    Cellular Component cytoplasm (more)
    Molecular Function hydrolase activity (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA il1rapl1a-201 (1)    Ensembl 4080
    il1rapl1a-202 (1)    Ensembl 1647
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM il1rapl1a No data available
    MARKER RELATIONSHIPS
    il1rapl1a Contained in: [BAC] CH211-165M3 (1), CH211-206L17 (1), CH211-243C19 (1), DKEY-265J8 (1) (order this)
    il1rapl1a Encodes: [EST] fi18g04
    [cDNA] MGC:152866 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001077576 (1) 4098 nt
    Genomic GenBank:CR749776 (1) 154131 nt
    Select Tool
    Polypeptide UniProtKB:E9QD35 (1) 744 aa
    Sequence Information (all 44)
    ORTHOLOGY for il1rapl1a ( Chr: 9 )
    CITATIONS (30)