Gene

il1rapl1a

ID
ZDB-GENE-061013-249
Name
interleukin 1 receptor accessory protein-like 1a
Symbol
il1rapl1a Nomenclature History
Previous Names
  • fi18g04
  • wu:fi18g04
  • zgc:152866 (1)
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to have NAD(P)+ nucleosidase activity; NAD+ nucleotidase, cyclic ADP-ribose generating; and interleukin-1 receptor activity. Predicted to be involved in negative regulation of exocytosis. Predicted to localize to cytoplasm; integral component of membrane; and plasma membrane. Is expressed in optic tectum and telencephalon. Human ortholog(s) of this gene implicated in intellectual disability and non-syndromic X-linked intellectual disability. Orthologous to human IL1RAPL1 (interleukin 1 receptor accessory protein like 1).
Genome Resources
Note
None
Expression
All Expression Data
from Yoshida et al., 2008
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With il1rapl1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
non-syndromic X-linked intellectual disability 21 Alliance Mental retardation, X-linked 21/34 300143
Associated With il1rapl1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000157 Toll/interleukin-1 receptor homology (TIR) domain
Domain IPR003598 Immunoglobulin subtype 2
Domain IPR003599 Immunoglobulin subtype
Domain IPR007110 Immunoglobulin-like domain
Domain IPR041416 IL-1Ra-like, immunoglobulin domain
Family IPR004074 Interleukin-1 receptor type I/II
Family IPR015621 Interleukin-1 receptor family
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamily
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
Domain Details Per Protein
Protein Length IL-1Ra-like, immunoglobulin domain Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Immunoglobulin subtype Immunoglobulin subtype 2 Interleukin-1 receptor family Interleukin-1 receptor type I/II Toll/interleukin-1 receptor homology (TIR) domain Toll/interleukin-1 receptor homology (TIR) domain superfamily
UniProtKB:A0A2R8QPU9 695
UniProtKB:E9QD35 744
UniProtKB:E9QFM7 549
UniProtKB:B6ZK76 701
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations