Gene

dclk1a

ID

ZDB-GENE-061013-124

Name

doublecortin-like kinase 1a

Symbol

dclk1a Nomenclature History

Previous Names

dcamkl1 (1)
dclk1
wu:fc51f11
zgc:153709

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in axon extension and protein localization to nucleus. Predicted to act upstream of or within intracellular signal transduction and protein phosphorylation. Predicted to be active in cytoplasm. Orthologous to human DCLK1 (doublecortin like kinase 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Di Stazio et al., 2020

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With dclk1a Human Ortholog

No data available

Associated With dclk1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR008271	Serine/threonine-protein kinase, active site
Binding_site	IPR017441	Protein kinase, ATP binding site
Domain	IPR000719	Protein kinase domain
Domain	IPR003533	Doublecortin domain
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily
Homologous_superfamily	IPR036572	Doublecortin domain superfamily

Domain Details Per Protein

Protein	Length	Doublecortin domain	Doublecortin domain superfamily	Protein kinase, ATP binding site	Protein kinase domain	Protein kinase-like domain superfamily	Serine/threonine-protein kinase, active site
UniProtKB:Q08BH4 InterPro	472
UniProtKB:A0A8M9QGM9 InterPro	346
UniProtKB:E9QBD0 InterPro	770
UniProtKB:A0A8M3AWX7 InterPro	720

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	dclk1a-201 (1) Ensembl	Ensembl	785 nt	Select Tool ZFIN BLAST
mRNA	dclk1a-202 (1) Ensembl	Ensembl	3,286 nt	Select Tool ZFIN BLAST
mRNA	dclk1a-203 (1) Ensembl	Ensembl	2,294 nt	Select Tool ZFIN BLAST
mRNA	dclk1a-204 (1) Ensembl	Ensembl	1,097 nt	Select Tool ZFIN BLAST
mRNA	dclk1a-206 (1) Ensembl	Ensembl	2,333 nt	Select Tool ZFIN BLAST
mRNA	dclk1a-207 (1) Ensembl	Ensembl	1,272 nt	Select Tool ZFIN BLAST
ncRNA	ottdart00000061452 (1) Ensembl	Ensembl	887 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations