ZFIN is now using GRCz12tu for Genomic Data
Gene
spire1a
- ID
- ZDB-GENE-061013-119
- Name
- spire-type actin nucleation factor 1a
- Symbol
- spire1a Nomenclature History
- Previous Names
-
- si:ch211-215i13.1
- si:zc215i13.1
- zgc:153436
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable microtubule binding activity. Predicted to be involved in several processes, including cytoskeleton organization; cytoskeleton-dependent cytokinesis; and positive regulation of double-strand break repair. Predicted to be located in cleavage furrow. Predicted to be active in cell cortex and cytoplasmic vesicle membrane. Orthologous to human SPIRE1 (spire type actin nucleation factor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | KIND domain | Protein Spire | Protein Spire homolog 1, FYVE-related domain | Zinc finger, FYVE/PHD-type | Zinc finger, RING/FYVE/PHD-type |
|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3AL19 | InterPro | 736 | |||||
| UniProtKB:A0A8M3AKA9 | InterPro | 772 | |||||
| UniProtKB:A0A0R4ITV6 | InterPro | 775 | |||||
| UniProtKB:A0A8M3B3M7 | InterPro | 766 | |||||
| UniProtKB:Q1LYM3 | InterPro | 761 | |||||
| UniProtKB:A0A8M2B6B0 | InterPro | 767 | |||||
| UniProtKB:A0A0R4IHM3 | InterPro | 781 | |||||
| UniProtKB:A0A8M2B6P4 | InterPro | 751 | |||||
| UniProtKB:A0AB32T739 | InterPro | 752 | |||||
| UniProtKB:A0AB32T7K9 | InterPro | 745 | |||||
| UniProtKB:A0AC58HYC8 | InterPro | 406 | |||||
| UniProtKB:A0ABF7PBB1 | InterPro | 722 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
spire1a-201
(1)
|
Ensembl | 3,770 nt | ||
| mRNA |
spire1a-202
(1)
|
Ensembl | 2,666 nt | ||
| mRNA |
spire1a-203
(1)
|
Ensembl | 2,684 nt | ||
| mRNA |
spire1a-204
(1)
|
Ensembl | 2,576 nt | ||
| mRNA |
spire1a-205
(1)
|
Ensembl | 2,615 nt | ||
| mRNA |
spire1a-206
(1)
|
Ensembl | 2,621 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers