ZFIN ID: ZDB-GENE-061013-109
Gene Name: 3-phosphoinositide dependent protein kinase 1a
Gene Symbol: pdpk1a    Nomenclature History

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Previous Names: im:7158209, zgc:153787

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and peptidyl-serine phosphorylation. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human PDPK1 (3-phosphoinositide dependent protein kinase 1).
Genome Resources: Alliance (1),  Gene:768202 (1),  Ensembl(GRCz11):ENSDARG00000062304 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7158209]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa5221 Point Mutation Unknown Splice Site ENU
sa20114 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38407 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH pdpk1a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH pdpk1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process protein phosphorylation (more)
    Molecular Function ATP binding (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA pdpk1a-201 (1)    Ensembl 2392
    pdpk1a-202 (1)    Ensembl 5027
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pdpk1a No data available
    MARKER RELATIONSHIPS
    pdpk1a Contained in: [BAC] DKEY-235I8 (1) (order this)
    pdpk1a Encodes: [EST] IMAGE:7158209 (1)
    [cDNA] MGC:153787 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001077344 (1) 2403 nt
    Genomic GenBank:CT573452 (1) 149560 nt
    Select Tool
    Polypeptide UniProtKB:F1R447 (1) 536 aa
    Sequence Information (all 13)
    ORTHOLOGY for pdpk1a ( Chr: 3 )
    CITATIONS (20)