ZFIN ID: ZDB-GENE-061009-13
Gene Name: glutamate receptor, metabotropic 3
Gene Symbol: grm3    Nomenclature History

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Previous Name: si:ch211-233h19.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Predicted to have group II metabotropic glutamate receptor activity. Predicted to be involved in G protein-coupled glutamate receptor signaling pathway and regulation of glutamatergic synaptic transmission. Predicted to localize to integral component of plasma membrane. Is expressed in brain and retinal neural layer. Orthologous to human GRM3 (glutamate metabotropic receptor 3).
Genome Resources: Alliance (1),  Gene:565256 (1), 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
a281 Complex Unknown Unknown CRISPR
la013354Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19195 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa36575 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-grm3 1
    CRISPR2-grm3 1
    CRISPR3-grm3 1
    CRISPR4-grm3 1
    PHENOTYPE
    Data: Fig. S4 from Thyme et al., 2019
    Observed in:
    DISEASE ASSOCIATED WITH grm3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH grm3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process G protein-coupled receptor signaling pathway (more)
    Cellular Component integral component of membrane (more)
    Molecular Function G protein-coupled receptor activity (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA grm3-201 (1)    Ensembl 2928
    Browsers: NCBI
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM grm3 No data available
    MARKER RELATIONSHIPS
    grm3 Contained in: [BAC] CH211-276C1 (1), DKEY-5I3 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001128343 (1) 2817 nt
    Genomic GenBank:CT025888 (1) 134613 nt
    Select Tool
    Polypeptide UniProtKB:A3KPM6 (1) 884 aa
    Sequence Information (all 12)
    ORTHOLOGY for grm3 ( Chr: 18 )
    CITATIONS (21)