ZFIN ID: ZDB-GENE-060929-894
Gene Name: tRNA-yW synthesizing protein 5
Gene Symbol: tyw5    Nomenclature History

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Previous Names: im:7148946, zgc:154110

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have several functions, including iron ion binding activity; protein homodimerization activity; and tRNA binding activity. Predicted to be involved in wybutosine biosynthetic process. Is expressed in immature eye; midbrain; optic vesicle; and retina. Orthologous to human TYW5 (tRNA-yW synthesizing protein 5).
Genome Resources: Alliance (1),  Gene:557725 (1),  Ensembl(GRCz11):ENSDARG00000069672 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (6 images) from Thisse et al., 2004 [IMAGE:7148946]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa13117 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17249 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH tyw5 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH tyw5 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process wybutosine biosynthetic process (more)
    Cellular Component cellular_component (more)
    Molecular Function 2-oxoglutarate-dependent dioxygenase activity (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA tyw5-201 (1)    Ensembl 1870
    ncRNA tyw5-002 (1)    Ensembl 770
    tyw5-003 (1)    Ensembl 941
    tyw5-004 (1)    Ensembl 322
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tyw5 No data available
    MARKER RELATIONSHIPS
    tyw5 Contained in: [BAC] DKEY-191G15 (1) (order this)
    tyw5 Encodes: [EST] IMAGE:7148946 (1), fb06a04 (1)
    [cDNA] MGC:154110 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001077543 (1) 1666 nt
    Genomic GenBank:CT867952 (1) 212473 nt Blast at MegaBLAST
    Polypeptide UniProtKB:F1Q971 (1) 326 aa
    Sequence Information (all 14)
    ORTHOLOGY for tyw5 ( Chr: 9 )
    CITATIONS (21)