Gene

cenpe

ID
ZDB-GENE-060929-860
Name
centromere protein E
Symbol
cenpe Nomenclature History
Previous Names
  • wu:fc06a10
  • zgc:152925 (1)
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to enable microtubule binding activity and plus-end-directed microtubule motor activity. Predicted to be involved in microtubule-based movement and mitotic cell cycle. Predicted to be active in microtubule. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 13. Orthologous to human CENPE (centromere protein E).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from Yu et al., 2020
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cenpe Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
primary autosomal recessive microcephaly 13 Alliance ?Microcephaly 13, primary, autosomal recessive 616051
Associated With cenpe Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019821 Kinesin motor domain, conserved site
Domain IPR001752 Kinesin motor domain
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036961 Kinesin motor domain superfamily
Domain Details Per Protein
Protein Length Kinesin motor domain Kinesin motor domain, conserved site Kinesin motor domain superfamily P-loop containing nucleoside triphosphate hydrolase
UniProtKB:F1RDY0 317
UniProtKB:F1R0G3 170
UniProtKB:F1QUW6 199
UniProtKB:Q08CM3 317
UniProtKB:F1R7B6 171
UniProtKB:E7F2U4 2690
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations