Gene
cenpe
- ID
- ZDB-GENE-060929-860
- Name
- centromere protein E
- Symbol
- cenpe Nomenclature History
- Previous Names
-
- wu:fc06a10
- zgc:152925 (1)
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to have ATP-dependent microtubule motor activity, plus-end-directed and microtubule binding activity. Predicted to be involved in microtubule-based movement and mitotic cell cycle. Predicted to localize to microtubule. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly 13. Orthologous to human CENPE (centromere protein E).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from Yu et al., 2020
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
?Microcephaly 13, primary, autosomal recessive | 616051 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR019821 | Kinesin motor domain, conserved site |
Domain | IPR001752 | Kinesin motor domain |
Family | IPR027640 | Kinesin-like protein |
Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Homologous_superfamily | IPR036961 | Kinesin motor domain superfamily |
Domain Details Per Protein
Protein | Length | Kinesin-like protein | Kinesin motor domain | Kinesin motor domain, conserved site | Kinesin motor domain superfamily | P-loop containing nucleoside triphosphate hydrolase |
---|---|---|---|---|---|---|
UniProtKB:A0A8M6YXU4
|
2352 | |||||
UniProtKB:A0A8M2BFG2
|
2668 | |||||
UniProtKB:E7F2U4
|
2690 | |||||
UniProtKB:A0A8M2BFG4
|
2626 |
Interactions and Pathways
No data available
Plasmids
No data available