ZFIN ID: ZDB-GENE-060929-756
Gene Name: transmembrane protein 178
Gene Symbol: tmem178    Nomenclature History

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Previous Name: zgc:153181

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 11 Mapping Details/Browsers
Description: Predicted to be involved in negative regulation of osteoclast differentiation and regulation of cytosolic calcium ion concentration. Predicted to localize to endoplasmic reticulum membrane. Is expressed in lateral line ganglion. Orthologous to human TMEM178A (transmembrane protein 178A).
Genome Resources: Alliance (1),  Gene:767702 (1),  Ensembl(GRCz11):ENSDARG00000020758 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 4 figures (10 images) from Rauch et al., 2003 [cegs2522]
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1210 Point Mutation Unknown Premature Stop ENU
sa9980 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa27806 Point Mutation Unknown Splice Site ENU
    sa41870 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH tmem178 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH tmem178 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of osteoclast differentiation (more)
    Cellular Component endoplasmic reticulum membrane (more)
    Molecular Function molecular_function (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA tmem178-201 (1)    Ensembl 2289
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tmem178 No data available
    MARKER RELATIONSHIPS
    tmem178 Contained in: [BAC] DKEY-31D5 (1) (order this), DKEY-218G22 (1) (order this)
    tmem178 Encodes: [EST] cegs2522 (1) (order this)
    [cDNA] MGC:153181 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001076640 (1) 2168 nt
    Genomic GenBank:BX323548 (1) 222367 nt Blast at MegaBLAST
    Polypeptide UniProtKB:F1QFK6 (1) 301 aa
    Sequence Information (all 14)
    ORTHOLOGY for tmem178 ( Chr: 11 )
    CITATIONS (22)