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ZIRC
ZFIN ID: ZDB-GENE-060929-644
Gene Name: transmembrane protein 88 b
Gene Symbol: tmem88b    Nomenclature History

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Previous Name: zgc:153314

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have PDZ domain binding activity. Predicted to be involved in negative regulation of canonical Wnt signaling pathway. Predicted to localize to the plasma membrane. Orthologous to human TMEM88 (transmembrane protein 88).
Genome Resources: Alliance (1),  Gene:100004517 (1),  Ensembl(GRCz11):ENSDARG00000069388 (2)
GENE EXPRESSION
All Expression Data: Fig. 7 from Eve et al., 2017
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH tmem88b HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH tmem88b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process negative regulation of canonical Wnt signaling pathway (more)
Cellular Component integral component of membrane (more)
Molecular Function PDZ domain binding (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR033354 (1)
  • InterPro:IPR033355 (1)
  • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA tmem88b-201 (1)    Ensembl 1309
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tmem88b No data available
    MARKER RELATIONSHIPS
    tmem88b Contained in: [BAC] DKEY-85K7 (1) (order this)
    tmem88b Encodes: [cDNA] MGC:153314 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001077144 (1) 1311 bp
    Genomic GenBank:BX005336 (1) 233826 bp Blast at MegaBLAST
    Polypeptide UniProtKB:E7F115 (1) 235 aa
    Sequence Clusters UniGene:81736 (1)
    Sequence Information (all 13)
    ORTHOLOGY for tmem88b ( Chr: 7 )
    CITATIONS (17)