ZFIN ID: ZDB-GENE-060929-220
Gene Name: zgc:153426
Gene Symbol: zgc:153426    Nomenclature History

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Previous Names: fj41e11, wu:fj41e11

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have GTP binding activity. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to localize to the cytoplasm and microtubule. Human ortholog(s) of this gene implicated in complex cortical dysplasia with other brain malformations 6. Orthologous to human TUBB (tubulin beta class I).
Genome Resources: Alliance (1),  Gene:767746 (1),  Ensembl(GRCz11):ENSDARG00000104436 (1)

Nomenclature Note: This gene is characterized by full length cDNAs isolated as part of the Zebrafish Gene Collection (ZGC). When more is known about the gene, the current nomenclature will be replaced with more traditional zebrafish gene nomenclature. The prefix `zgc:' indicates that this gene is represented by cDNAs generated by the ZGC project.

GENE EXPRESSION
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH zgc:153426 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH zgc:153426 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process microtubule-based process (more)
Cellular Component cytoplasm (more)
Molecular Function GTPase activity (more)
GO Terms (all 10)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Binding_site IPR013838 Beta tubulin, autoregulation binding site
Conserved_site IPR017975 Tubulin, conserved site
Domain IPR003008 Tubulin/FtsZ, GTPase domain
Domain IPR018316 Tubulin/FtsZ, 2-layer sandwich domain
Family IPR000217 Tubulin
Family IPR002453 Beta tubulin
Homologous_superfamily IPR008280 Tubulin/FtsZ, C-terminal
Homologous_superfamily IPR023123 Tubulin, C-terminal
Homologous_superfamily IPR036525 Tubulin/FtsZ, GTPase domain superfamily
Homologous_superfamily IPR037103 Tubulin/FtsZ, C-terminal domain superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA zgc:153426-201 (1)    Ensembl 1752
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM zgc:153426 No data available
MARKER RELATIONSHIPS
zgc:153426 Contained in: [BAC] CH211-198P19 (1), DKEY-27E20 (1) (order this)
zgc:153426 Encodes: [EST] fj41e11
[cDNA] MGC:153426 (1), MGC:192666 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001076715 (1) 1768 nt
Genomic GenBank:CR847534 (1) 211145 nt Blast at MegaBLAST
Polypeptide UniProtKB:F1R4K1 (1) 444 aa
Sequence Information (all 20)
ORTHOLOGY for zgc:153426 ( Chr: 3 )
CITATIONS (19)