Gene

zgc:153993

ID
ZDB-GENE-060929-176
Name
zgc:153993
Symbol
zgc:153993 Nomenclature History
Previous Names
  • im:7148473
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have channel activity; protein heterodimerization activity; and protein homodimerization activity. Predicted to be involved in apoptotic signaling pathway; mitochondrial fusion; and positive regulation of apoptotic process. Predicted to localize to mitochondrial outer membrane. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; ataxia telangiectasia; colon adenocarcinoma; and colorectal cancer. Orthologous to human BAX (BCL2 associated X, apoptosis regulator).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With zgc:153993 Human Ortholog
No data available
Associated With zgc:153993 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR002475 Bcl2-like
Family IPR026298 Bcl-2 family
Homologous_superfamily IPR036834 Bcl-2-like superfamily
Domain Details Per Protein
Protein Length Bcl-2 family Bcl2-like Bcl-2-like superfamily
UniProtKB:Q08BX9 204
UniProtKB:A9JSY8 204
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations