Gene

prkag2a

ID
ZDB-GENE-060929-160
Name
protein kinase, AMP-activated, gamma 2 non-catalytic subunit a
Symbol
prkag2a Nomenclature History
Previous Names
  • zgc:153329
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Predicted to contribute to AMP-activated protein kinase activity. Predicted to be involved in cellular response to glucose starvation; protein phosphorylation; and regulation of catalytic activity. Predicted to localize to cytoplasm; nucleotide-activated protein kinase complex; and nucleus. Human ortholog(s) of this gene implicated in Wolff-Parkinson-White syndrome; glycogen storage disease; hypertrophic cardiomyopathy; hypertrophic cardiomyopathy 6; and lethal congenital glycogen storage disease of heart. Orthologous to human PRKAG2 (protein kinase AMP-activated non-catalytic subunit gamma 2).
Genome Resources
Note
None
Expression
All Expression Data
Fig. 6 from Yang et al., 2017
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With prkag2a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
hypertrophic cardiomyopathy 6 Alliance Cardiomyopathy, hypertrophic 6 600858
lethal congenital glycogen storage disease of heart Alliance Glycogen storage disease of heart, lethal congenital 261740
Wolff-Parkinson-White syndrome Alliance Wolff-Parkinson-White syndrome 194200
Associated With prkag2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000644 CBS domain
Family IPR039170 5'-AMP-activated protein kinase subunit gamma-2
Domain Details Per Protein
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations