Gene

fat3a

ID

ZDB-GENE-060929-1254

Name

FAT atypical cadherin 3a

Symbol

fat3a Nomenclature History

Previous Names

fat3
zgc:153498
zmp:0000000581 (1)

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Description

Predicted to have calcium ion binding activity. Involved in cartilage morphogenesis. Predicted to localize to integral component of membrane and plasma membrane. Is expressed in Meckel's cartilage; palatoquadrate cartilage; and pectoral fin. Orthologous to human FAT3 (FAT atypical cadherin 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from Le Pabic et al., 2014

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Le Pabic et al., 2014
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With fat3a Human Ortholog

No data available

Associated With fat3a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018097	EGF-like calcium-binding, conserved site
Conserved_site	IPR020894	Cadherin conserved site
Domain	IPR000742	EGF-like domain
Domain	IPR001791	Laminin G domain
Domain	IPR001881	EGF-like calcium-binding domain
Domain	IPR002126	Cadherin-like
Homologous_superfamily	IPR013320	Concanavalin A-like lectin/glucanase domain superfamily
Homologous_superfamily	IPR015919	Cadherin-like superfamily
PTM	IPR000152	EGF-type aspartate/asparagine hydroxylation site

Domain Details Per Protein

Protein	Length	Cadherin conserved site	Cadherin-like	Cadherin-like superfamily	Concanavalin A-like lectin/glucanase domain superfamily	EGF-like calcium-binding, conserved site	EGF-like calcium-binding domain	EGF-like domain	EGF-type aspartate/asparagine hydroxylation site	Laminin G domain
UniProtKB:A0A8M9Q0H4 InterPro	4124
UniProtKB:A0A8M6Z1C0 InterPro	3944
UniProtKB:A0A2R8QAL3 InterPro	4601
UniProtKB:X1WCY4 InterPro	4578
UniProtKB:F1QA09 InterPro	4546
UniProtKB:A0A8M9QLG7 InterPro	4569