ZFIN ID: ZDB-GENE-060929-1210
Gene Name: neuralized E3 ubiquitin protein ligase 1Ab
Gene Symbol: neurl1ab    Nomenclature History

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Previous Names: neurlb, zgc:153175

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Predicted to have ubiquitin protein ligase activity. Predicted to be involved in negative regulation of Notch signaling pathway and nervous system development. Predicted to localize to the plasma membrane and postsynaptic density. Orthologous to human NEURL1 (neuralized E3 ubiquitin protein ligase 1).
Genome Resources: Alliance (1),  Gene:767739 (1),  Ensembl(GRCz11):ENSDARG00000061773 (1)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1120 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH neurl1ab HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH neurl1ab VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of Notch signaling pathway (more)
    Cellular Component plasma membrane (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR001841 Zinc finger, RING-type
    Domain IPR006573 Neuralized homology repeat (NHR) domain
    Family IPR037962 Neuralized
    Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA neurl1ab-201 (1)    Ensembl 2553
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM neurl1ab No data available
    MARKER RELATIONSHIPS
    neurl1ab Contained in: [BAC] CH73-210H12 (1), CH73-288O11 (1)
    neurl1ab Encodes: [cDNA] MGC:153175 (1), MGC:191391 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001076708 (1) 2519 nt
    Genomic GenBank:CU928227 (1) 106845 nt
    Select Tool
    Polypeptide UniProtKB:F1QZ44 (1) 521 aa
    Sequence Information (all 18)
    ORTHOLOGY for neurl1ab ( Chr: 17 )
    CITATIONS (16)