Gene

rnf220a

ID
ZDB-GENE-060929-1006
Name
ring finger protein 220a
Symbol
rnf220a Nomenclature History
Previous Names
  • zgc:153254
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to enable ubiquitin protein ligase activity. Involved in spinal cord patterning. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy. Orthologous to human RNF220 (ring finger protein 220).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Ma et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rnf220a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Leukodystrophy, hypomyelinating, 23, with ataxia, deafness, liver dysfunction, and dilated cardiomyopathy 619688
Associated With rnf220a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001841 Zinc finger, RING-type
Domain IPR031824 E3 ubiquitin-protein ligase RNF220, middle domain
Domain IPR040178 E3 ubiquitin-protein ligase RNF220, RING finger
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Domain Details Per Protein
Protein Length E3 ubiquitin-protein ligase RNF220, middle domain E3 ubiquitin-protein ligase RNF220, RING finger Zinc finger, RING/FYVE/PHD-type Zinc finger, RING-type
UniProtKB:A8WHS2 577
UniProtKB:B0S679 138
UniProtKB:F1QY42 232
UniProtKB:Q08CD0 307
UniProtKB:A0A2R8QNR6 260
UniProtKB:A0A286YC01 223
UniProtKB:B0S678 197
UniProtKB:A0A2R8QHI7 216
UniProtKB:E9QJE4 70
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations